Sentence examples for dna slides from inspiring English sources

To unwind the DNA, slides were immersed in an alkaline buffer (NaOH, EDTA).

To allow the unwinding of the DNA, slides remained in contact with the high pH buffer for 20 min.

For co-denaturation of the probe and target DNA, slides were placed for 5 minutes on a hotplate preheated to 73°C and than transferred overnight to a warmed hybridisation chamber at 37°C.

PCNA is a DNA sliding clamp that interacts with several proteins involved in cell cycle control, DNA methylation, DNA replication and DNA repair including mismatch repair [ 7].

Besides the homotrimeric PCNA DNA sliding clamp, a heterotrimeric DNA sliding clamp exists, Rad9-Rad1-Hus1 Rad9-Rad1-Hus1 Rad9-Rad1-Hus1y and structurally highly related to PCNA [22], [23].

A central component of the replisome is represented by the DNA sliding clamps.

For instance, this may involve ubiquitylation of the alternative DNA sliding clamp 9-1-1 (see below) [21].

Monoubiquitination of the DNA sliding clamp, PCNA, plays a central role in the control of damage bypass during replication.

The homotrimeric DNA sliding clamp Proliferating Cell Nuclear Antigen (PCNA) encircles the DNA and acts as a critical processivity factor for the replicative polymerases δ and ε.

The DNA sliding clamps PCNA and 9-1-1 are critical docking stations for proteins involved in diverse processes such as replication, recombination, and DNA damage management.

This effect is attributed to autoinhibition of sequence-specific DNA binding by the C-terminal domain due to increased DNA sliding [20], [21].