Fan, L. & Yao, Y. G. MitoTool: A web server for the analysis and retrieval of human mitochondrial DNA sequence variations.
Thus, a SNP marker assay may be an appropriate alternative because SNPs represent the most abundant DNA sequence variations in the genome.
They sequenced the Nav1.8 gene from the grasshopper mouse, and compared it to that of the common mouse, to identify multiple DNA sequence variations that confer insensitivity to scorpion venom.
Further genetic analyses may identify DNA sequence variations, in the HERV-K genes themselves, and others that interact with them, which might make the virus more prone to reactivation.
Several efforts are focusing on the search for DNA sequence variations underlying common/complex diseases that constitute a real burden in terms of public health measures.
The DNA amplification products were subjected to SSCP analysis to identify the DNA sequence variations between the susceptible strain and resistant populations.
GWASs rely on linkage disequilibrium to detect associations between DNA sequence variations (markers) and phenotypes.
A study involving more than 200,000 people worldwide has identified 29 DNA sequence variations in locations across the human genome that influence blood pressure.
These SNPs and indels represented 22 combinations of DNA sequence variations and were named A1 to A22 (allele 1 to allele 22, Table 2).
Additional examination of the two genes in anoxeria-prone families gave the researchers a handle on which DNA sequence variations conferred the most risk.
In the study, published Tuesday in the journal PLoS Medicine, researchers focused on several DNA sequence variations on chromosome 9p21, which they call "one of the most robust genetic associations for cardiovascular disease".
