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There are also fewer papers studying the actual physical effect of nano-materials on DNA, regardless of their biological effects.
DART-PCR was designed to differentiate products amplified from RNA and DNA regardless of the presence of introns.
By using solvatofluorochromic deoxyguanosine analogue 4c, we have developed highly thymine (T) selective fluorescent DNA probes that can sense T opposite 4c in a target DNA regardless of the flanking sequences.
PCR and qPCR based testing with universal primers is to be used as the first screen of clinical specimens to identify those samples containing bacterial DNA, regardless of species, to alert the clinician that infection is highly probable in those patients testing positive.
For example, the lac repressor can bind non-specifically to DNA regardless of its sequence [26].
MspI cleaves DNA regardless of methylation status of the internal cytosine and serves as a control for digestion efficiency.
Similar(41)
Because AlkB binds to DNAs regardless of their sequences, the complementary strand in dsDNA serves as a noncompetitive inhibitor for the repair, leading to the preference of AlkB for ssDNA over dsDNA.
In contrast, the combination of Gensolve and NucleoSpin (GN and Gn) increased the DNA yield while preserving DNA quality, regardless of the use of ethanol in the precipitation step (Table 2, p < 0.05).
As shown in Fig. 4a, the shift distances of DNA fragments were negatively related with the length of DNA fragments regardless of adding GO in agarose gel.
These data suggested that 2.5 μM SAHA was capable of inhibiting cell proliferation in both TM10 and TM2H cell lines by blocking DNA synthesis, regardless of their differences in the number of cells synthesizing DNA.
Moreover, any DNA sequence, regardless of its source and composition can replicate in these systems, arguing that no specific DNA sequence is required to initiate DNA replication [6].
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