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The tool allowed him to quickly find a type of DNA pattern that looks like stutters among billions of chemical letters in human DNA.
The first group of algorithms utilizes a generative probabilistic representation of the nucleotide positions to discover a consensus DNA pattern that maximizes the information content score.
The consensus patterns, detected as words and related clusters of words, provide a DNA pattern that is strongly represented in these promoters.
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Researchers identified the strain by analyzing DNA patterns that can be compared with those from other regions of the world, according to Dr. Christopher Braden, a C.D.C. epidemiologist.
Global DNA demethylation is known to be essential for germ cells to establish allele-specific DNA methylation pattern that is necessary for appropriate genomic imprinting.
Patient 13's isolate showed a DNA fingerprint pattern that differed from patterns A and B by a single band.
Therefore, the diabetic epigenotype that we have identified represents a hyperglycemia-associated DNA methylation pattern that is persistent despite multiple cell culture passages under normoglycemic conditions.
We found that underlying airway disease was associated with a specific DNA methylation pattern that was not altered by HRV infection.
Consistently, APL patients are characterised by a specific DNA methylation pattern that is distinctive from other AML subtypes (Figueroa et al, 2010).
Endometrium is a unique tissue undergoing cyclic breakdown and regeneration, and similarly to other tissues and cell types [ 18, 19], has its own distinct DNA methylation pattern that is influenced by cyclic hormonal changes [ 20].
For a given transcription factor and an experimentally identified set of transcription factor binding sites, or a set of co-regulated promoters, computational methods can be applied to identify the DNA sequence pattern that is recognized by the transcription factor.
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CEO of Professional Science Editing for Scientists @ prosciediting.com