Sentence examples for dna mutation status from inspiring English sources
To further examine the possible pretranscriptional mechanisms of ERAP1 downregulation, ERAP1 DNA mutation status was analyzed alongside existing data on various single nucleotide polymorphisms.
Univariate analysis showed no association between mitochondrial DNA mutation status or mitochondrial gene expression and any of the examined clinicopathologic parameters.
In the present study we have compared the DNA sequence mutation status of the genes KRAS, BRAF, PIK3CA, PTEN, and TP53 in tumor samples from patients younger than 50 years at diagnosis and without known hereditary syndromes, and stratified according to MSI status and elderly CRC patients.
CMJT provided DNA samples and mutation status.
Despite these caveats, our analysis of the circulating DNA PIK3CA somatic mutation status does not support the hypothesis that tumors with PIK3CA mutations have improved responsiveness to MK-2206.
In patients with heterogeneous mutation status, DNA cocktails were prepared and genotyped.
The relationship between KRAS/ BRAF mutation status, DNA mismatch repair (MMR) status, clinicopathological variables and overall survival was analysed.
On the basis of the results of this study, we conclude that it is feasible to use serum DNA to detect EGFR mutation status and evaluate its potential as a predictor of response to EGFR-TKI.
The aim of the current study was to establish the frequency of KRAS and BRAF mutations in GC in a large multicentre study, investigate the relationship between KRAS/ BRAF mutation status, DNA MMR status and clinicopathological variables including survival, and compare findings between GC from different geographic regions.
(d) Subgroup classification from MS-MIMIC showed total concordance with the reference subgroup (from 450k and GoldenGate DNA methylation arrays and CTNNB1 mutation status) after applying a classification confidence probability threshold (NC –non classifiable).
We tested 60 FFPE breast DNA samples with known PIK3CA mutation status (48 cases had one or more PIK3CA mutations, and 12 were wild type) as identified by PCR-mass spectrometry.
