Sentence examples for dna may act from inspiring English sources
The recognition element to which a transcription factor binds is of functional significance because DNA may act as an allosteric ligand influencing the conformation and thus the activity of the transactivation domain of the binding protein, as well as the recruitment of other proteins to the enhanceosome.
First, the isolated viral DNA may act as a unique form of this virus intermediate.
The DNA may act in two ways.
It is possible that noncellular markers in blood, particularly of circulating DNA, may act as improved markers of residual disease.
In fact, even if our results do not reflect the situation in vivo, they are enormously relevant since they clearly dissociate -for the first time- levels of mtROS production in isolated mitochondria and longevity in Drosophila melanogaster, indicating that other mitochondrial factors such as the presence of polymorphisms in mitochondrial DNA may act as longevity regulators.
Thus the cell can be modeled as a vector field in which the mechanically linked cytoskeleton-NM-DNA may act as transducers of mechanical information.
Finally, DNA methylation may act independently of the transcription factor BCL11A to repress fetal hemoglobin production.
Rather we propose that cumulative DNA damage may act as one of the age-related risk factors contributing to degenerative disorders such as ALS.
The found motif may be related to a sequence-specific interaction of this protein region with DNA, which may act as a modulator of the interaction of HP1 with H3K9 methylation.
They may also play a pivotal role in maintaining genome and strain identity in this naturally competent organism: since multiple strains are often present in the same niche, DNA methylation may act to limit recombination between strains and thus preserve diversity.
For example, prior studies suggest that in the epileptic hippocampus, global increases in DNA methylation may act to dampen hyperexcitability through downregulation of gene expression, as DNMT inhibition in area CA1 with zebularine resulted in a decreased latency to seizures when administered prior to SE and increased cell excitability in epileptic animals.
