Exact(3)
DOI: http://dx.doi.org/10.7554/eLife.09115.005 In addition to total HIV-1 DNA levels, we also measured integrated HIV-1 DNA levels.
Unlike reports measuring DNA levels, we did not detect higher JAK2V617F mRNA expression levels in samples from ET patients with respect to PV.
To evaluate the correlation of different treatments with reductions in HBV DNA levels, we used HBV DNA (Log10 IU/ml) as the dependent variable and treatment duration as the independent variable.
Similar(57)
That's why, at the fundamental DNA level, we're always going to have problems.
At the DNA level, we observed the association between KIR genes, especially KIR3DS1 and KIR3DL1, and HIV disease progression.
In addition to the aforementioned results on the DNA level, we observed that higher level expression of KIR3DS1 mRNA was in LTNP group, and that higher level expression of KIR3DL1 mRNA was in TP group.
To confirm the effect of knockdowns on G1/S transition at the DNA level, we measured incorporation of 7-AAD into the DNA of single cells by flow cytometry 18 hours after EGF stimulation.
Therefore, to test whether codon pairs are biased because of translational effects or because of mechanisms operating at the DNA level, we calculated the ratio of observed and expected co-occurrences of two trinucleotides at the genome level.
To determine whether a pangene absent at the annotated protein level was nevertheless present at the DNA level, we demanded a threshold of 80% identity across the entire sequence length of the query protein.
At the DNA level, we consider all changes in which an edited cytosine is replaced by thymine as losses of editing, because this editing is no longer needed to synthesize the correct protein sequence.
Besides providing an overview of the NGS-based approaches most frequently used to study the molecular basis of human diseases at DNA level, we discuss the principal challenges and applications of NGS in the field of human genomics.
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