Sentence examples for dna is positioned from inspiring English sources

The duplex segment of primer-template DNA is positioned in the central chamber of the clamp loader where it is stabilized by basic residues and amino-terminal helix dipoles lining the interior surface of the clamp loader spiral.

However, there is currently no structural data on the OC and the ITC and thus it remains unclear how DNA is positioned on Pol II after promoter opening, and which structural rearrangements occur during formation of ITC intermediates containing short RNAs.

The spacer sequences acquired from foreign DNA are positioned between host repeats, and transcribed together as CRISPR RNA (crRNA).

The design of the current investigation was to determine whether the efficiency and fidelity of TLS by pol β could be modulated in the context of a gapped substrate in which the downstream DNA was positioned appropriately for interaction with the flexible amino-terminal 8 kDa domain.

These alleles are not expected to produce functional proteins, as the T-DNAs are positioned upstream of or in the region encoding the SET domain, suggesting that they are null alleles.

The DNA insert is positioned downstream and in-frame with a sequence encoding the (His 6-tag and an enterokinase cleavage recognition site.

Only one of them can be specifically conjugated to a DNA polymerase enzyme that is positioned right at the pore opening.

The NF-κB-II DNA-binding site, which is positioned from-105 to-96 relative to the transcription start site, was inactivated by exchanging the sequence 5'-GGGACTTTCC-3' with 5'-CCCCCCCCCC-3' through a PCR strategy with a mutagenic primer on the pBlue3'LTR and pBlue5'LTR intermediate plasmids as described previously [75].

Therefore, the (6 S,8 R,11 stereoisomermer of the HNE-derived exocyclic 1, N-dG adduct 3, which exists predominantly in duplex DNA as cyclic hemiacetal 10, is positioned to facilitate interstrand cross-linking in the 5′-CpG-3′ sequence.

At the final stages of DNA binding and cleavage (Figure 5C), the quinolone resistance sites (Ser 79 and Asp 83, which are located within the helix α4 bound to the minor groove of the DNA molecule) will be positioned next to the 3'-end of the cleaved DNA strand with Ser 79 being closest to the point of cleavage (Figure 5C).

Through the genome browser, biomarker DNA sequences can be positioned using BLAT/BLAST alignment tools or possibly through keyword searches.