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The abasic site on the DNA is coordinated by the two Mg2+ ions, of which one also attacks the hydroxyl nucleophile (left panel).
The relative cellular content of mitochondrial DNA (mtDNA), as determined by the ratio of the mitochondrial 12S rRNA gene to the nuclear β-F1-ATPase gene did not show significant deviations from the initially observed value (dotted line in Fig. 1A), suggesting that synthesis of nuclear and mitochondrial DNA is coordinated during cell cycle progression.
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For example, one could imagine a cause and effect role, in which the activation of transposable elements would lead to DNA damage and the DNA damage response is coordinated through PRMT5-dependent splicing regulation.
Our data illustrate that the timing of post-fertilization DNA methylation acquisition is coordinated across the Dlk1-Dio3 locus, although methylation at the Dlk1 locus appears more labile (data herein) [ 11].
Repair of base-pair mismatches is coordinated with DNA replication to ensure correction of the newly synthesized DNA strand.
UNG expression is coordinated with DNA replication.
In general, SRS2 is expressed at low levels and its expression is coordinated with DNA synthesis genes, which are induced at the G1-S transition.
These replication-dependent histone mRNAs are cell cycle regulated, and their expression is coordinated with DNA replication during the "synthesis-phase" or S-phase of the cell cycle.
Telomerase action is coordinated with conventional DNA replication of the bulk of the telomere [ 4] taking place from replication forks originating from subtelomeric origins of DNA replication [ 5, 6].
To determine whether DSB formation is coordinated with bulk DNA replication during meiS in budding yeast, we exposed cells to increasing doses of the replication inhibitor hydroxyurea (HU) and measured the kinetics of DNA replication and DSB formation (using a rad50S mutation to prevent DSB repair).
Since every cell contains the same strand of DNA, the quantum computer is in very cell, and it is coordinated with every other.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com