This is absorbed in DNA, with the formation of UV-specific dipyrimidine photoproducts.
UVB radiation reaches the epidermis and the upper dermis where it is absorbed by DNA, trans-urocanic acid (trans-UCA), and cell membranes.
Though the majority of UVB radiation (∼95%) is blocked in the atmosphere, it has a significant contribution to the biological effects of UV radiation since it is absorbed by cellular DNA.
Aluminum in antiperspirants is absorbed, can bind DNA, is estrogenic and is found in greater concentrations in the upper outer quadrant.
UVBR is absorbed primarily by DNA, but also by proteins and lipids, causing damage that can lead to mutations and cell death (Tevini, 1993).
In addition to inactivation of DNA, far-UV's increased photon energy is absorbed by peptide and disulfide bonds, which breaks the bonds and causes irreparable damage [ 17].
UVB is absorbed by proteins or DNA of epidermis, whereas UVA radiation penetrates deeply into the skin and reaches the lower epidermis and dermal fibroblasts.
In a direct action, a secondary electron, which results from photon absorption, interacts with and is absorbed by a biomolecule, such as DNA, RNA, or proteins.
During exposure to sunlight solar radiation with wavelengths of 290 315 nm penetrate into the skin and are absorbed by proteins, DNA and RNA as well as 7-dehydrocholesterol., Most of this UVB radiation is absorbed in the epidermis and as a result when exposed to sunlight most of the vitamin D3 that is produced in the skin is made in the living cells in the epidermis.
