Sentence examples for dna interactions of from inspiring English sources
Because transcription factor inhibition is complex but is an attractive area for anticancer and antiparasitic drug development, we have evaluated the DNA interactions of additional derivatives of DB1255 to gain an improved understanding of the biophysical chemistry of complex function and inhibition.
To evaluate the biological preference of chiral drugs for inherently chiral target DNA, interaction of 1 3 with calf thymus DNA in Tris HCl buffer was studied by various biophysical techniques which reveal that all these complexes bind to CT DNA non-covalently via electrostatic interaction.
The DNA interaction of these complexes was tested at pH = 7.2, by using electronic absorption spectra and viscosity measurements.
The DNA interaction of these complexes was investigated by electronic absorption spectroscopy, viscosity, cyclic voltammetry and gel electrophoresis measurements.
The DNA interaction of the complexes (3 5) was investigated by UV Vis spectroscopy and cyclic voltammetry (CV).
Taken together, our genome-wide analysis of the comprehensive DNA interaction of PPARγ and its heterodimerization partner, RXR provides an enhanced understanding of global functions of this NHR pair.
Radiotherapy is believed to function either by direct ionization or indirectly by DNA interaction of radicals formed by water ionization.
The sequence-specific, covalent DNA interaction of brostallicin in comparison with tallimustine was analysed by the Taq polymerase stop assay.
The preparation and DNA interaction of IHF mimics should be a useful tool for further understanding of protein/DNA recognition on the molecular level.
In this context, we have recently described a photo-uncaging strategy for controlling the non-covalent DNA interaction of DNA-binding agents, such as those shown in the Fig. 1.
Here we report on the DNA interaction of a synthetic compound that specifically binds to a G·C bp in the minor groove of DNA by using an azabenzimidazole moiety.
