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TADSir was modeled using a set of algorithms designed to simulate DNA interactions based on nearest neighbor base stacking interactions and Gibb's free energy differences between helical coil and folded DNA states.
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However, STAMP as well as footprintDB detect and predict TF-DNA interactions based on known data.
There has been significant interest in developing computational methods for identifying amino acid residues that participate in protein-DNA interactions based on combinations of sequence, structure, evolutionary information, and chemical and physical properties.
It was not, however, absolutely required for inhibiting the TBP-DNA interaction, based on experiments with the Mot1 latch mutant containing the C-terminal ATPase domain.
In the studies of DNA protein interactions based on DNA CT, relatively high protein concentrations were used, making the methods poorly competitive, when compared to other methods not relying on electrochemistry, such as gel electrophoresis.
We divided protein telomere DNA interaction data based on whether the particular proteins were known telomere-associated proteins or identified through telomere ChIP studies.
The Arabidopsis multinetwork consists of genes (nodes) connected by edges that represent interactions based on: (1) metabolic pathways (2) protein-protein interactions and (3) protein-DNA regulatory interactions.
Herein, in this chapter, we summarize the recent progress in the study of protein NP, DNA NP, and lipid NP interactions based on various spectroscopic techniques.
Are these interactions based on biophotons?
Support for protein-protein interactions and protein-DNA interactions are based on information from DIP [ 49], BIND [ 52] and Transfac [ 53].
Using a highly specific and quantitative protein-DNA interaction screen based on the SILAC technology the Mann group identifies a protein termed muscle growth regulator (MGR).
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