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Application of DNA-loaded liposomes instead of single signal DNA increases the sensitivity of iLAMP drastically.
DNA increases the viscosity and adhesiveness of lung secretions [ 6].
For example, the amount of HR HPV DNA increases the grade of the lesion.
Previous reports consistently suggest that inclusion of >30 ng purified DNA increases the success rate up to 96% [ 29].
The ability to run samples with as little as 10 ng of parasite DNA increases the number of field samples for which whole genome analysis is possible.
This was particularly important for the historical samples because their lower DNA concentrations and fragmented DNA increases the likelihood of allelic drop-out particularly for large alleles.
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The binding of chloro/morpholino-PTQ to DNA increased the melting temperature by about 1.5 7.0 °C.
The corresponding color change is shown in Figure 2B; as the concentration of DNA increased, the color of the mixed solution changed from purple gradually to red.
The well-known ones such as UV damage and smoking mutate the DNA, increasing the odds of cancer.
The simple mix of NLS-CTHD among these novel transfection enhancing peptides with DNA increased the gene transfer potency of cationic liposomes more efficiently with no additional cytotoxicity.
Oxidation damages DNA, increasing the risk of initiation; antioxidants can defend against this.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com