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A more practical idea might turn out to be a Daedalus proposal to use the "junk DNA" incorporated in the genomes of all living creatures, including microbes, as a vehicle for storing vast quantities of information.
These results provide experimental evidence that in vitro studies can be used to estimate the in vivo immunostimulatory activity of CpG DNA incorporated into DNA nanostructures.
Quantitative determination of biofilm formation was also evaluated in the presence of desoxiribonuclease I (DNase I) and DNA, incorporated in the medium.
In Rubin's lab, postdoctoral fellow James Noonan first created a library of Neandertal DNA incorporated into live bacteria that reproduce the DNA, creating an endless supply.
These results strongly suggest that the length of continuous DNA incorporated into B. subtilis is most probably greater than 1271 kb.
The plasmid DNA incorporated in the scaffolds showed a burst release in the first week and a sustained release for the other 2 weeks.
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We designed a protocol for reliable ultrastructural identification of proliferating cells in a tissue volume using DNA-incorporated 5-bromo-2-deoxyuridine (BrdU) as a marker.
DNA synthesizing cells in colonies were determined in 4 cases using monoclonal antibodies against DNA-incorporated bromodeoxyuridine (BrdUrd).
DNA-incorporated I-IUdR was shown to be very efficacious (5- to 7-log cell killing) in the radiotherapy of small-animal malignancies [ 6].
Cell kinetics in the growing, regressing and dormant phase were studied by immunocytochemical detection of DNA-incorporated bromodeoxyuridine (BrdUrd) in tissue sections.
UNG is highly specific for processing of uracil in DNA but also excises DNA-incorporated 5-fluorouracil (5-FU), a uracil analog used in cancer therapy (Pettersen et al. 2011).
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