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Study of TCAST1 satellite DNA dynamics at the level of T. castaneum natural populations revealed low differences in mutational profiles, but no significant difference in the monomer size, organization, and copy number was detected (Feliciello et al. 2011).
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Most of what we know about satellite DNA dynamics is at the resolution of large blocks of satellite DNA on chromosome arms.
Assembly issues with repetitive DNA have stymied our understanding of satellite DNA evolutionary dynamics at the genomic level [ 21].
In conclusion, our investigation presents the evidence for the significant variation of satellite DNA profiles at the population level and suggests the potential influence of satellite DNA dynamics on evolution of species.
DNA dynamics in tight spaces challenge nature's nanomachines.
Patient EM11 displayed complex circulating tumor DNA dynamics.
We used hairpin bisulfite sequencing [ 21, 22] to investigate the replication-dependent DNA methylation pattern dynamics at specific repetitive elements such as the L1Md_Tf (hereafter referred to as L1), major satellites (mSat) and IAPLTR1 (IAP).
Finally, we assessed ccf-DNA dynamics in surgical CRC patients.
Here, we choose the polymerase β (pol β)–DNA complex to study the water dynamics at its tight binding interface.
Over the past two decades, researchers have used DNA as a model system to study polymer dynamics at the molecular level.
It will be very interesting to understand how the high nucleosome sequence preferences, the high intrinsic TF-DNA binding affinities, and chromatin remodelers together determine nucleosome dynamics at vitro+/vivo- promoters.
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