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DNA dynamics in tight spaces challenge nature's nanomachines.
Cells use ring-like structured protein complexes for various tasks in DNA dynamics.
TFs are proteins that directly interact with DNA, and to some extent what we display here is the map of the cell "hardware" that drives DNA dynamics.
The foundation for future studies has been laid by careful experimentation and computer simulation of DNA dynamics in bulk or locally linear flows of many types.
TPT also alters the DNA dynamics.
However, considering the strong structural similarity of RecA and Rad51 nucleoprotein filaments, and the fact that the mechanistic strategy of RecA likely relies on intrinsic DNA dynamics [44], we expect that the qualitative conclusions drawn for RecA regarding local sequences differences will also stand for hRad51.
Similar(40)
Finally, we assessed ccf-DNA dynamics in surgical CRC patients.
It is likely that the demethylation in PLEKHG6 does not directly regulate gene expression, because, despite the differences in DNA methylation dynamics in SRC and PLEKHG6, their expression dynamics are similar.
Open image in new window Figure 1 DNA methylation dynamics in mouse preimplantation embryos.
Open image in new window Fig. 1 DNA methylation dynamics and human phenotypic variations.
In terms of sperm DNA fragmentation dynamics, the highest intensity of sperm DNA damage occurred in the first 6 h of incubation.
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