Exact(3)
Comparison of normalized Σ PMi) and Σ MMi) intensities over the i chips for each probe indicates that the probes matching the draft A lyrata genome are the most sensitive markers of DNA differentiation, as expected (figure 2).
This indicates that probes matching the draft genome are the most sensitive markers for detecting DNA differentiation, but also that the 2.48 million other unique probes contain useful information.
One possibility is that only mtDNA is truly divergent in the absence of any strong nuclear DNA differentiation.
Similar(57)
For histological quantification (DNA damage, differentiation), at least 30 representative transverse heart sections from ventricles and atria were used.
However, this is seen as far from crucial in the light of the observed DNA marker differentiation.
Megakaryocytic precursors, unlike other cells, continue to synthesize DNA during differentiation.
DNA amounts, differentiation, and mineralization were monitored to assess maturation stage.
In addition, p21 also participates in other diverse processes including transcription, DNA repair, differentiation, senescence and apoptosis.
We have used the coefficient of variation (CV) as a measure of DNA methylation differentiation level, as it is a variability measure that controls for the mean methylation.
However, we didn't observe expression changes for other three genes, which may indicate that their DNA methylation differentiation may not have caused change of gene expression levels.
Indeed, more recently several p63 post-translational modifications have been recognized, acting either during response to DNA damage, differentiation or embryonic development (24– 24).
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