Sentence examples for dna decrease the from inspiring English sources
NGS can produce digital signals directly from the complementary DNA, decrease the risk for false-positive data, and correspond to the existing genomic sequence.
Modifying the transgene DNA to exclude nonmethylated CpG motifs, typical of bacterial DNA, decreases the immune response and may increase transgene expression [ 75, 76].
Including the masked ranges in the calculation of total surveyed DNA decreases the mutation density from 1/294 to 1/351 kb for EMS and from 1/265 to 1/316 kb for Az-MNU.
Human stathmin (STMN1) antisense DNA decreases the growth of K562 cells [ 66], so possibly up-regulation of STMN1 has a stimulatory effect on growth.
It is tempting to speculate that the flexibility of bubble or kinked DNA decreases the distance between the lesion sites and thereby increases the probability of an intersegmental transfer event between the two duplex arms of the DNA.
We also observed that as the amount of DNA decreased, the reproducibility of the reaction was lower, giving a higher inter-tube and inter-assay variation, mainly in the 1 30 (2 ng) and 1 40 (1.5 ng) dilutions (data not shown).
A 10-fold excess amount of genomic DNA decreased the overall call rate of each sample to by about 80% and another study revealed that samples with less than 50 ng/μl genomic DNA show low overall call rates [ 15].
As shown in Figure 5, while coadministration of bic 155 with CRT/E7 DNA decreased the number of IFN-γ-secreting E7-specific cytotoxic T cells generated by CRT/E7 (* p < 0.01), coadministration of I 155 with CRT/E7 DNA significantly improved the E7-specific CD8+ T cell-mediated immune response generated by CRT/E7 (** p < 0.05).
Nuclear proteins binding to the DNA could decrease the accessibility of the DNA for DNase I, thus leading to regions on the DNA protected from digestion.
Also, a very low amount of template DNA might decrease the number of recombinations during PCR.
In addition, mismatches at the nucleotide level between the probe on the array and the hybridized DNA can decrease the hybridization efficiency.
