Sentence examples for dna compound from inspiring English sources

Both compounds exhibit some intercalation in DNA, compound 2 being the more intercalative one, with a lower fraction (65%) of molecules accessible to anionic quencher.

15 This inhibition is significant as thymidylate synthase catalyzes conversion of deoxyuridine 5-monophosphate to the DNA compound thymidine 5-monophosphate.

In this paper, we define a set of in vitro, DNA-based molecular transformations that can be linked to each other in such a way that the product of one transformation can activate or inhibit the production of one or several other DNA compounds.

The docking energies of the DNA-compound adducts varied from − 23.84 to − 30.96 kJ/mol, and the adducts were stabilized by H-bonding and hydrophobic attractions.

RAPTA-C was found to hydrolyze fastest and showed the highest reactivity toward the DNA model compound, whereas KP418 was the most stable compound in both these respects.

The absorbance of DNA + compound mixture was increased (loss of hypochromecity) after 2 and 24 h of mixture which illustrated DNA damage.

Previous studies [ 116, 117] were reported in BC focusing on action of DNA methyltransferase compound inhibitors.

As mentioned, AnV staining already occurs in an early stage of apoptosis, while the DNA intercalating compound PI only can enter late apoptotic cells.

The analysis also identified several false-positive compounds with very high Z scores, namely known DNA binding compounds of red colour (doxorubicin and derivatives, crystal violet, homidium bromide, propidium iodine, pararosalinine pamoate).

This approach is designed to maximize the sensitivity for correctly identifying DNA reactive compounds while providing a framework to reduce the number of compounds that need to be synthesized, purified and subsequently tested in an Ames assay.

The intrinsic fluorescence of compounds 1 and 2 can be used to monitor interactions with DNA and compounds behaviour when encapsulated in liposomes.