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The enzyme specifically introduces negative supercoiling in a process that must coordinate fuel consumption with DNA cleavage and religation and with numerous conformational changes in both the protein and DNA components of a large nucleoprotein complex.
A similar trend was observed in DNA components, of which 30% were sediment-exclusive, 12% subsurface-exclusive and 7% DCM-exclusive (Additional file 9: Figure S5).
This platform is further diversified by replacement of canonical histones with histone variants and the chemical modification of both histone and DNA components of the nucleosome.
Two classes of highly abundant repetitive sequences, satellite DNAs (satDNAs) and transposable elements (TEs), represent major DNA components of many centromeric regions.
Because satDNAs are the major DNA components of heterochromatin, differences in their composition can be linked with reproductive isolation and speciation (Bachmann et al. 1989).
In addition to the conserved stem-loop sequence and adjacent regions referred to as common region stem-loop (CR-SL), the NCR of the seven non- rep DNA components of each isolate contained further conserved domains.
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GC analysis of random NRC-1 sequences shows two small peaks at about 56% and 59%, which likely reflect the DNA component of pNRC100 and pNRC200, and a large peak at about 70%, likely reflecting the DNA component of the chromosome.
Several subfamilies of centromere repeats are hypomethylated in sperm compared with oocytes (Fig. 3c), including ALR/Alpha, which is the major DNA component of centromeres in primates, whereas the BSR/Beta subfamily is hypermethylated in sperm (Fig. 3d).
The suggested learning activity "Use genome data to identify stop and start codons and known protein coding sequences" (Scottish Qualifications Authority 2014b) is directly addressed by the "DNA" component of 4273π, as used in the current study.
Alpha-satellite DNA (AS) is a main DNA component of primate centromeres, consisting of tandemly repeated units of ∼170 bp.
Alpha satellite DNA is a repetitive sequence known to be a major DNA component of centromeres in primates (order Primates).
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