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Because of the consistent differences between the WGA DNA and the native unamplified DNA, characterization of the genomic region of interest, as described here, will be necessary to ensure the reliability of genotyping results from WGA DNA.
However, because there are consistent differences between the WGA DNA and the native unamplified DNA, characterization of the genomic region of interest, as described here, will be necessary to ensure the reliability of genotyping results from WGA DNA.
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This method is of particular interest for technologies such as strand sequencing of DNA and characterization of other charged polymers such as proteins.
While additional analyses are needed to investigate whether this hypermethylation is a by-product of gene expression or participates to its regulation, even to a low extent, our study provides the first detailed DNA methylation characterization of VRN-A1.
Frank, H.-G. et al. Cytogenetic and DNA-Fingerprint Characterization of Choriocarcinoma Cell Lines and a Trophoblast/Choriocarcinoma Cell Hybrid.
Finally, these primers were also designed to allow amplification of short DNA segments for characterization of poorly preserved material and highly degraded DNAs from herbarium samples.
Liu, L. et al. The archaeal DNA primase: biochemical characterization of the p41-p46 complex from Pyrococcus furiosus.
Although the nucleotide sequence of phaC from B. vietnamiensis was available following complete genomic DNA sequencing, functional characterization of the gene has not been reported.
An internal probe was then used on KpnI-digested DNA for further characterization of ES cell clones that were positive for homologous recombination.
Therefore, understanding the role of repetitive DNA and the characterization of their structure, organization and evolution is essential.
Host factors like sex and age strongly influence biological variation of DNA methylation, but characterization of these relationships is still limited, particularly in young children.
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