Sentence examples for dna can induce from inspiring English sources

Double-strand breaks (DSBs) in chromosomal DNA can induce both homologous recombination (HR) and non-homologous end-joining (NHEJ).

For example, the commonly used Hoechst 33342 stain, which binds to the minor groove of the double-stranded DNA can induce single-strand DNA breaks5, or DRAQ5 (deep red fluorescing bisalkylaminoanthraquinone) the nuclear stain that intercalates with the cell's DNA can influence chromation organization and lead to histone dissociation6.

In addition to CpG motifs, runs of deoxyguanosine (dG) residues in DNA can induce B cell activation and promote macrophage cytokine expression by adjacent CpG motifs.

Together, these observations suggest that DNA can induce innate as well as adaptive immune responses and promote the pathogenesis of SLE because of its intrinsic immunostimulatory activity.

In pre-autoimmune mice, immunization with bacterial DNA can induce anti-DNA autoantibody production, suggesting a role in initiating this response.

Furthermore, P. gingivalis DNA can induce IL-1, IL-6 and TNFα production in a monocytic cell line through TLR9 [40].

Rather, dysfunctional telomeres and/or accumulated DNA damage can induce a DNA damage response leading to a phenotype in postmitotic neurons that resembles cell senescence in multiple features.

Similarly, antibiotics causing DNA damage can induce an SOS DNA repair response [ 22, 23, 25].

The target p53 DNA hybridization can induce the isothermal circular strand-displacement polymerization even without any chemical modification and other DNA sequences.

It has been demonstrated that DNA vaccine can induce both specific T cell responses (CTL and blast transformation) and specific antibodies in mice immunized with pcDNA-TCI.

These findings show that DNA vaccination can induce all of the components required for humoral immunity and also provide a system for in depth analysis of factors that influence the development of antibody responses.