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We also examined the expression of the small-heterodimer partner (SHP), which can heterodimerise with activated receptors and prevent transactivation of DNA as it lacks a DNA binding domain [27].
Base excision repair helps ensure that mutations are not incorporated into DNA as it is copied.
But AZT was able to insinuate itself into the virus's DNA as it formed, and later it was used in lower doses.
At its core, densely packed high-precision equipment will encase a cavernous vacuum chamber, in which a super-hot cloud of heavy hydrogen will rotate faster than the speed of sound, twisting like a strand of DNA as it circulates.
He can put the bull to several cows each year for natural procreation, but the impact is limited by the breeding season and the dilution of the bull's DNA as it combines with the cows' inferior genetic profiles.
Usually the triplication of a genome would be a considerable handicap, saddling a plant with three times as much DNA as it needs.
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This first "Falstaff" in L.A. for the company's music director, James Conlon, is in his DNA as well: It's one of the first operas he saw as a kid and also the first opera he conducted professionally.
Since Liu et al labelled the RNA, rather than the DNA, as done here, it is possible that the DNA template strand register may be shifted in the published 4 and 5 nt structures (PDB codes 3RZO, 3RZD).
This also concerns mitochondrial DNA (mtDNA), as it may accumulate DNA damage due to high level of reactive oxygen species (ROS) in its environs and less efficient DNA repair in comparison with nuclear DNA [ 10].
High resolution melting (HRM) involves the precise monitoring of the change in fluorescence caused by the release of an intercalating DNA dye from a DNA duplex as it is denatured by increasing temperature.
Monitoring the melting curve of the amplicon involves detecting the change in fluorescence intensity induced by the release of an intercalating DNA dye from a DNA duplex as it denatures at high temperatures.
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Justyna Jupowicz-Kozak
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