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This suggests that the shuffling algorithm indeed does identify biologically or clinically distinct divisions of patients in most cases.
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But in a post on his blog, the Kidney Doctor, Dr. Ajay K. Singh, an influential nephrologist at Brigham & Women's Hospital in Boston, questioned whether the division of patients based on whether they undergo dialysis "makes any sense from a safety perspective".
The expression profile of these 38 probe sets was used to perform a clustering of the 68 tumors and led to the division of patients into two clusters (Fig. 6A).
Our division of patients into groups with increased and decreased summarized SF-36 scores is arguable.
This analysis does not depend upon any a priori division of patients into neglect and non-neglect groups.
The division of patients into multiple risk groups and the late occurrence of many events further burden such trials.
In the latest 2009 TNM system, diaphragm is taken as a division of patients with IVC tumor thrombus.
The division of patients according to their answers to questions 3 and 7 allows us to conduct a summary analysis of the variability in patient attitudes.
Presently, there exists no commonly accepted definition of this form of "individualised medicine"; the lowest common denominator is actually the "division of patients (groups) by biomarkers" [ 4].
Treatment decisions are often made through the division of patients into subgroups using biomarkers based on gene expression assays or immunohistochemical assays.
The division of patients with SUDs and psychiatric disorders into separate treatment clinics is based on tradition and not on professional consensus.
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Justyna Jupowicz-Kozak
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