Sentence examples for division pathway from inspiring English sources

The finding suggests that therapies under development that target the cell division pathway may hold great promise for NF1 patients, who develop numerous noncancerous tumors and have a highly elevated risk for several kinds of cancer.

The initial observation that the ER physically wraps around mitochondria and facilitates mitochondrial constriction at nascent division sites added a novel player to the mitochondrial division pathway [ 42].

Information on proliferation rates is also necessary for the development of therapeutic agents, some of which may be targeted directly at specific points in the cell division pathway.

Drp1-mediated membrane remodeling is subject to regulation at various points in the division pathway, including targeting of Drp1 to the MOM and modulation of the GTP-regulated assembly, constriction, and disassembly of the Drp1 helix.

Indeed, based on the recent addition of novel, unexpected players to the mitochondrial division pathway in both yeast and humans, it is clear that our knowledge of the entire complement of proteins that comprise and regulate the division complex is far from complete.

At the proteome level we mainly observed changes in mitochondrial translation, cell division pathways and proteins related to cell cycle progression.

Our findings highlight the complex nature of the AZT effect on airway cells, which involves up-regulation of lipid/cholesterol biosynthetic pathways, suppression of cell division pathways, and specific modulation of inflammatory genes, including down-regulation of mucin production.

As Tip60 plays an important role in regulating apoptosis [43], [44] and double stranded break repair [45], [46], [47], [48], lethality may result, at least in part, by defects in multiple cell division pathways.

DNA replication, recombination and repair pathways of dnaA and ruvA as well as cell division pathways mreB, parA and ftsA were also found to be essential.

The yeast census was also enriched for proteins involved in cytokinesis and cell division, pathways where a role for Tel1/Mec1 kinases was previously hinted.

SCF Fbw7) degrades proteins that function in cellular growth and division pathways, including c-Myc, cyclin E, Notch, and c-Jun (Welcker and Clurman, 2008).