Exact(1)
Inactivation of tumour suppressors and activation of proto-oncogenes leads to uncontrolled growth and cell division, hallmarks of tumour development.
Similar(59)
Inhibition of such a mechanism by specifically developed drugs can be a useful and highly specific approach to inhibit cell movement and division, two hallmarks of metastasizing cancer cells.
Dysregulation of cell division is a hallmark of all cancers.
Given that mis-regulation of cellular division is the hallmark of cancer, it is striking that miRNAs with highly population-differentiated alleles are observed to be significantly enriched for regulation of mitotic pathway genes including genes such as S100A8 and P2RX3 whose expression profiles are currently used as biomarkers for multiple cancers.
Mr. Bush, meanwhile, traveled to Pennsylvania, where he accused Mr. Gore of making "fear, division and misrepresentation" the hallmarks of the final stage of his campaign.
The combination of these alterations promotes deregulated cell division, one of the hallmarks of the cancer phenotype [1].
Internal division has been the hallmark of Democratic politics for over a century.
Natural selection operates on populations and results in changes in function and expression for genes expressed in the normally non-reproductive workers, effecting morphological, physiological, and behavioral differentiation resulting in division of labor, the hallmark feature of social insects.
Chromosomal instability, a state of frequent chromosome loss and gain during cell division [4], is a hallmark of human cancers.
Asymmetric division, which is a hallmark of stem cells, is not restricted to a specific cell compartment.
Division of labor, a hallmark of advanced insect sociality, has long attracted attention from biologists, as these systems of polyphenism are some of the most elaborate in the animal kingdom [ 1- 3].
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