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Judge Rakoff determined that the jurors intended the award to be around $2.9 million, but that a division error by one of the jurors led to the lower amount.
The high rate of cell division error implies that the regulation of mitosis, particularly the activity of cell division checkpoints, might be different from that in somatic cells.
Measurement of each lung parameter showed the stable tidal volume division (error < 10%) in all patients.
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Because the mutation rate in lymphoid precursors has been estimated to be ∼10−6 per cell division, errors in DNA replication are likely to accumulate during cell divisions1,2.
The aim of this study was to investigate the origin and nature of chromosome 21 (cell) cell division errors in human IVF embryos.
Different possibilities account for the sex-specific differences: first, the differences in the recombination patterns between male and female meiosis; second, more permissive checkpoints in females than males; third, the age-related loss of chromosome cohesion in female gametes; and fourth, the difference in the ability to detect the consequences of meiotic division errors [5], [11] [15], [34].
JIL performed and analyzed cell division errors and micronuclei formation.
It gives rise to chromosomal instability, as seen in a high rate of chromosomal division errors.
During cell division errors in DNA replication occur that are critical for the formation of mutations.
Thus, the rapid maternally driven embryonic divisions were much more sensitive to division errors than were the later zygotic divisions.
While previous screens had used fixed endpoint assays to identify cytoskeletal regulators whose silencing led to cytokinesis failure (e.g., [ 10]), here we aimed to combine fixed data with live imaging to identify siRNAs that caused more subtle division errors.
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CEO of Professional Science Editing for Scientists @ prosciediting.com