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The terminal DNA at chromosome ends, known as telomeres, progressively shorten with each cell division and limit the replicative life span of human cells in culture [ 3].
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Further, all experiments were performed in conditions promoting asynchronous cell division and limiting acidosis.
Immortalization is a necessary step toward the malignant transformation of normal human somatic cells, which have intrinsic mechanisms that monitor cell divisions and limit their life span.
Efforts were also made to coordinate investigations with an internal intelligence division and to limit the actions of officers suspected of helping to carry out kidnappings.
His insider's portrait of Syria's helicopter squadrons offers details of a military capacity that, while potent, is undermined by sectarian division and operational limits.
And refusing to call it what it is fosters division and hostility, and limits our empathy.
Thus, the mature erythrocytes lack DNA and are unable to produce RNA, rendering them incapable of division and repair and limiting the functional lifespan of the circulating red blood cell (RBC).
With regard to telomeres, their lengths are gradually reduced by cell division and, beyond a threshold limit value, cellular senescence is induced (D'adda di Fagagna et al. 2003; Takai et al. 2003; Herbig et al. 2004).
And refusing to call it what it is fosters division and hostility, and it limits our empathy.
The public health department was clustered predominantly by division, and the staff generally limited their information-seeking networks to a handful of peers within their division.
Thus, the telomere length can predict and limit the number of divisions a cell can undergo.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com