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To date, all of the currently approved antibodies are of the IgG isotype, which is further divided into four subclasses in humans (i.e., IgG1, IgG2, IgG3, and IgG4) (Brezski and Georgiou, 2016; Lefranc, 2001).
Until now, eighteen different isoenzymes of histone deacetylases (HDACs) are known which are divided into four subclasses.
This class contains 697 proteins and is further divided into four subclasses: Ligands (57 proteins), Other (272 proteins), Structural/Adhesion proteins (187 proteins) and Proteins of unknown function (181 proteins).
LTR retrotransposons can be further divided into four subclasses based on their sequence similarity and various structural features: Ty1/Copia, Ty3/Gypsy, BEL/Pao (also sometimes named only BEL or Pao) and DIRS [ 10].
Two distinct families of GEFs have been identified for Rho GTPase activation: the conventional Dbl-family (Hart et al., 1991) and the more recently identified DOCK180 family (Takai et al., 1996; Hasegawa et al., 1996; Erickson and Cerione, 2004), which is divided into four subclasses.
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The distribution is equally divided into three subclasses.
The population is divided into three subclasses: susceptible, infected, and recovered.
Depending on the details of the mission plan, the closed-loop hybrid system will be divided into two subclasses: sequential and non-sequential.
Compounds 1 15 and 48 52 are of type U and are divided into three subclasses based on the number of double bonds attached to the aromatic nucleus.
According to different conformations of ligand-bound PYLs, the PYLs family can be divided into three subclasses, among which the trans-dimeric subclass, represented by PYL3, reveals a distinct regulatory mechanism.
Class V is further divided into two subclasses based on the presence/absence of a cavity in an existing rudimentary horn, avoiding an extremely detailed subdivision [21, 45, 85, 91, 93, 94].
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CEO of Professional Science Editing for Scientists @ prosciediting.com