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In a sensitivity analysis we divided exposure at 90% percentile to compare those 10% of the participants who had the highest exposure levels to the remaining participants.
We divided exposure into three classes: none (never or missing), short (less than 10 years) and long (more than 10 years).
However, unlike the Michigan study, the Oswego findings were presented not as regression coefficients but as linear F-test results, which divided exposure into four ordinal categories.
We divided exposure periods into: any exposure (all exposures in the prenatal and postnatal periods), any prenatal exposure (preconception to birth), and any postnatal exposure (birth to 13 years).
27 29 In the three studies that divided exposure groups into interferon β-1a and β-1b, patients with interferon β-1b monotherapy exposure numbered only 10 21, 28 30 31 thereby limiting the statistical power to draw conclusions about the effects of interferon β-1b on pregnancy outcomes.
We further divided exposure periods into preconception (6-0 months before conception) and by trimester (first, 0-12 weeksecondond, 13-24 weeks; and third, 25 weeks to birth); and by postnatal period (0-2.9 years; 3-6.9 yeand; 7-12.9 7-12.9ars; table 1).
Similar(54)
To study combination effects, we divided exposures into two levels using the medians: 10 years for duration of jobs associated with pesticide exposure and 70 times for cumulative number of uses of any household pesticide products.
A nonlinear effect of organo-chlorines was investigated by dividing exposure into quartiles of the distribution.
We will also examine the presence of linear association by dividing exposure into multiple discrete categories (eg, by quintiles of exposure level or of exposed participants).
Dividing exposures into quartiles showed a significant exposure response relationship (Bono et al. 2012).
We considered several exposure metrics: cumulative exposure (log-transformed and untransformed), duration of exposure (log-transformed and untransformed), peak exposure, and average exposure (cumulative exposure divided by duration of exposure).
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