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RBs continue to enlarge but not divide in the presence of penicillin.
Replicative lifespan in budding yeast is assessed by determining the number of times cells divide in the presence of nutrients before they senesce and die [11] via an apoptotic-like mechanism [12].
Interestingly, at least some of the cells were able to divide in the presence of selenite though the division was delayed.
RNAi-directed depletion of septin subunits of the heterotrimer results in mitotic catastrophe similar to that seen when cells attempt to divide in the presence of TTFields [ 5].
PAX3 is a key determinant of somatic myogenesis and, is involved in the migration of progenitor cells to the dermomyotome region of the somite where they grow and divide in the presence of growth factors.
However, alterations that compromise ATR kinase signaling may be selected against since transformed cells may have an increased dependency on the ATR pathway, analogous to oncogene addiction, to continue to replicate and divide in the presence of replication stress.
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As shown in Fig. 4C, both Gfi1−/− and Gfi1+/+ HSC divided in the presence of SCF & IL7, documented by a decrease in fluorescence intensity.
The majority of LT-HSCs never divided in the presence of PD033299.
Cancer cells adapt to dividing in the presence of supernumerary centrosomes by clustering them at the poles of a bipolar spindle; however, in the process of organizing a bipolar spindle those cells may generate abnormal chromatid attachments that lead to aneuploidy (reviewed in [ 39, 42]).
Walled cells grow and divide normally in the presence of the antibiotic but the mutant FtsZ protein fails to support division in the absence of benzamide.
Additionally, these results refine our understanding of the control of germ cell fate: Constitutive GLP-1/Notch signaling or combined loss of gld-3 and nos-3 does not promote germ cell proliferation per se, but rather promotes an undifferentiated fate in which cells divide only in the presence of food.
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