Sentence examples for diversity of effector from inspiring English sources

We suggest that DnaE catalyzed PTS could be used to combine a given antibody with a diversity of effector proteins.

As the adenovirus vector promotes clonal expansion of CD8 + T cells that recognize a small number of epitopes derived from tumor antigens, the number and diversity of effector CD8 + T cells might not be sufficient to eliminate tumor cells completely.

Our results indicate that co-receptor-mediated tuning of the signalling pathways downstream of TCR engagement not only improves the dose-response pattern of CTL activation but also partially determines the diversity of effector functions mobilised at a given dose of antigen.

The position of NEMO within this pathway would therefore necessitate its ability to communicate with a large diversity of effectors to respond to these different stimuli.

The role of effectors in fungal pathogenicity and virulence is well established, and thus monitoring allelic diversity of effectors in evolving pathogen population and among races can assist in R gene deployment in cultivated varieties [ 38, 39].

However, our comparative genomics and phenotypic analyses do support that diversity in symbiotic functions of the X. bovienii bacterial strains differ due to the diversity of effectors and their regulation rather than the utilization of different mechanisms for interacting with hosts.

The functional diversity of macrophages is critical to orchestrate the variety of effector functions that range from inflammation and phagocytosis to immunoregulation and tissue remodeling.

This forms the basis of ' terminal reassortment', a hypothesis proposed to explain the diversity of bacterial effectors (Stavrinides et al., 2006).

The bacterial and archaeal CRISPR-Cas systems of adaptive immunity show remarkable diversity of protein composition, effector complex structure, genome locus architecture and mechanisms of adaptation, pre-CRISPR (cr RNA processing and interference.

In this issue, Goronzy and Weyand begin by exploring how the dynamics of T cell repertoire diversity promote the expansion of effector cells [ 7].

Based on recent knowledge on molecular mechanisms altered in other systemic inflammatory diseases, DSS may result from a complex pro-inflammatory network involving a diversity of innate immune effectors sustaining a secondary systemic inflammatory loop, leading in turn to vascular homeostasis breakdown and systemic microcirculatory failure characterizing DSS (Figure 4).