In both cases there is a metabolic flux diversion towards product formation.
When asked about proposed changes in the state's pot laws, DEA spokeswoman Casey Rettig told VICE in an email, "Outside of DOJ's priorities, our directive is to rely on state and local law enforcement agencies to address marijuana activity through their own regulatory structures to prevent the illegal diversion of product, along with the enforcement of their own narcotics laws".
The incidence of illicit diversion of pharmaceutical products is a worldwide problem associated with negative health consequences and with other crimes.
Designer drugs and high content modified release formulations have been exploited both in casual recreational drug abuse as well as, on a much larger scale, by the criminal diversion of these products for profit.
Bill Kilby is a freelance writer based in Los AnGiven.
We also reiterate here the importance of focusing and asking direct questions on the nature and patterns of drug intake, including medical products diversion and consumption of NPS, during clinical assessments [ 94].
Shapiro (2010a) defends that economists have measured diversion from one product to another using cross-elasticity of demand between two products, and agencies have used elasticities to measure "reasonable interchangeability".
This decision allowed those visiting either ADDOs or public clinics to receive the same dosage instructions and public health messages; however, NMCP was concerned that using the exact same packaging might result in significant product diversion from public facilities to ADDOs.
In addition, ChREBP is deactivated via activation of adenosine monophosphate-activated kinase (AMPK) that takes place in conditions where the AMP/ATP ratio is high, a consequence of increased diversion of the end products of glycolysis into fatty acid synthesis rather than oxidative phosphorylation (Hebbachi and Saggerson, 2013).
Some critics argue that parallel importing acts as a disincentive to differential pricing by research-based pharmaceutical companies due to a risk of diversion of low-cost products to lucrative, developed country markets; however, as Outterson notes "...empirical evidence to date does not indicate a sizable arbitrage market in ARVs from low income countries into the high income countries"[ 20].
