Although the MEIS-A domain was more ancient, the Meis partner also clearly acquired additional protein features, allowing the formation and therefore diversifying the activity of Hox/PBC/Meis networks in Metazoa.
In order to diversify the pharmacological activity of chalcones and extend the scaffold of topoisomerase and cathepsins B and L inhibitors, we have designed and synthesized total 18 chalcone compounds and tested their biological activity.
The additional presence of Meis allows revealing specific Pbx interaction motifs (SPIMs), which could be important for distinguishing and/or diversifying the embryonic activities of each Hox paralog group member.
The uniformity of this simple disaccharide repeat is then diversified by the activity of several other biosynthetic enzymes, including sulfotransferases with differing specificities, N-deacetylase/N-sulfotransferases (NDSTs), and an epimerase, eventually producing a polysaccharide sidechain of astonishing complexity [5], [6].
Trading activities in fact can help make banks less risky and more stable by diversifying the company's activities and revenue streams.
Aside from a big marketing effort, part of the turnaround has involved diversifying the house's activities: the Hôtel des Ventes also advises clients on inheritance claims and other issues.
Heuer says that one of his other priorities is to bolster CERN's fixed-target program into hadron, antimatter, and neutrino physics so as to diversify the lab's activities.
In recent years, however, as executives of the publicly held Tejon Ranch Company have sought to diversify the ranch's economic activity, three giant warehouses have sprouted near the freeway.
By developing the centre, KCC plans to provide the means to diversify the forest and wilderness activities available for economic development and job creation in predominantly remote Aboriginal communities.
Thus the need to diversify the scope of mentoring activities to include medical ethics, professionalism, personal support, research implementation, dissemination and translation into policy in order to impact health policies and service delivery and maximize the benefits to the mentors, mentees and the entire community.
Last December, the news site Al-Monitor reported that organ harvesting appears to be yet another way for the Islamic State to diversify the portfolio that fund its activities. .
