Sentence examples for diversified recognition from inspiring English sources

Quantitative isoform-profiling of highly diversified recognition molecules.

Thank you for sending your work entitled "Quantitative Isoform-Profiling of Highly Diversified Recognition Molecules" for consideration at eLife.

Reviewer 3: "In this manuscript titled 'Quantitative Isoform-Profiling of Highly Diversified Recognition Molecules', Schreiner and colleagues report a mass spectroscopy based method that permits quantitative measurement of different splice variants and isoforms of the highly diverse neurexin cell adhesion protein family.

Invertebrate immune systems have been shown to include highly diversified recognition systems, complex regulatory processes, and specific effectors [ 1– 5].

This does not necessarily mean that apiAP2 genes do not duplicate readily in apicomplexans, but rather that redundant copies of apiAP2 are quickly lost or diversified beyond recognition in part by selective pressure to reduce gene repertoires and genome sizes (Katinka et al., 2001) and due to higher rate of sequence divergence in parasites (Hafner et al., 1994).

To understand how novel TF specificity evolves, we combined phylogenetic, biochemical, and biophysical approaches to interrogate how DNA recognition diversified in the steroid hormone receptor (SR) family.

The pathogen may respond by acquiring a new effector protein to suppress this recognition or by diversifying away from recognition [ 7, 8].

Genes encoding recognition proteins diversified mainly by accumulating coding mutations, whereas genes encoding effector proteins diversified primarily through duplication (Sackton et al. 2007; Waterhouse et al. 2007).

Alternatively, as extracellular ribonucleases are very stable molecules, highly resistant to proteolytic degradation, they may have had a rigid structure that could have been an ideal starting scaffold for evolving an effector arsenal, in which the loop regions were subjected to positive selection allowing the CSEPs to diversify and avoid recognition by host surveillance factors (R-proteins).

With the decline and later demise of the coal industry from the 1950s, the city diversified its economy and received national recognition for its "Scranton Plan," which provided jobs through industrial expansion.

Most genes in the signal transduction pathways occur as single orthologous copies in each species' genome and are highly conserved, whereas genes encoding pattern recognition and effector proteins have diversified rapidly across species (Sackton et al. 2007).