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The results of figure 6 indicated that our method is applicable to comparison of significantly diversified organisms, namely two different strains of Anabaena.
The results showed that statistical method is capable of detecting global synteny relationship in genomes of related but significantly diversified organisms.
This Cryptochrome therefore appears to provide a missing link between the different functions of Cryptochromes in more diversified organisms 81.
The isoapostasy method will be applicable to more diversified organisms because, as stated above, our method includes statistics of long-distance relationship and is more robust to rearrangements and indels.
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Moreover, according to Woese and Kandler [ 9, 114], LUCA was a promiscuous community of organisms diversified to a certain extent in terms of physiology.
Since this ancestral time, two forms of life have co-developed [6]; cells that are ribosome-encoding organisms (REOs), diversified in three domains (Archaea, Bacteria, and Eukarya), and capsid-encoding organisms (CEOs) (bona fide viruses, parasites of the REOs).
The POPPY methodology represents a step in making optimal pathway-host matches, which is likely to become important as the practical range of host organisms is diversified.
Although it remains to be seen whether additional groups of marine organisms have diversified from deep to shallow-water environments, possible deep-water origins of other animal groups, such as neogastropod mollusks [14], [15] and reef fishes [27], suggest that the deep sea has contributed repeatedly to the formation of shallow-water communities.
This multitude of topics makes them an ideal model system for integrative research toward understanding why and how organisms diversify, offering the opportunity for integrating across disciplines, from genome organization through genes, molecular and developmental mechanisms to phenotypic and ecological effects.
Understanding how and why organisms diversify is a major goal in evolutionary biology [ 1 4].
In this review, we introduce the semi-aquatic bugs (Gerromorpha, Heteroptera) as original models well suited to study why and how organisms diversify.
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