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We cannot override the presence of other important cellular and ECM related characteristics such as chemical factors (presence of specific motifs, peptide, proteins, and growth factors) or the coexistence of diversified cells in several arrangements that would play important roles in the alteration of cellular responses to various drugs and biopharmaceuticals.
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The exchange of amastigotes between host cells would occur in a cascade of events, involving diversified cell lineages and culminating in the intracellular growth within macrophages.
Unlike in ovarian cancer, breast cancer is composed of more diversified subpopulation of cells suggesting stem cell like cells may exist.
Although there is a consensus that macrophages are a diversified set of cells, macrophage subtypes are still poorly characterized.
Intuitively, maintaining a diversified population of cells is costly in constant and unperturbed environments but can prove advantageous if the environment fluctuates, because a fraction of cells may then be readily adapted.
A diversified product offering including cell phones and telephones helped boost sales 22%, even in a downturn.
As a model system to study the function of this highly diversified and complex cell type, bone marrow-derived macrophages (BMDM) differentiated in vitro from bone marrow myeloid progenitors have enabled gene function studies in macrophages in general, as well as providing an abundant source of primary cells that are otherwise difficult to obtain.
Vascular cell Jiang, X., Tian, W., Sung, Y. K., Qian, J., Nicolls, M. R. 2014; 6 (1): 5-? Macrophages are highly plastic hematopoietic cells with diversified functions related to their anatomic location and differentiation states.
The presence of diversified and unequivocally eukaryotic cells is documented in sediments ∼1.5 Ga of age (Javaux et al. 2001; Knoll et al. 2006), followed by eukaryotic algae at ∼1.2 Ga (Butterfield 2000).
Involvement of conservative molecular modules and cellular mechanisms in the widely diversified processes of eukaryotic cell morphogenesis leads to the intriguing question: how do similar proteins contribute to dissimilar morphogenetic outputs.
Interestingly, we observed diversified expression patterns in different cell types of meiocytes (cell columns and dissociated meiocytes) resulting from the examined promoters (Table 1).
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