The large panel of interactions (touching, shaking, voice dictation, positioning …) and the diversification of interaction devices can be seen as a factor of flexibility albeit introducing incidental complexity.
Evolutionary thinking in support of protein interaction analysis can reveal the conservation and diversification of interacting modules in cellular pathways.
Hence, our finding of the unexpected diversity of V1Rs may provide insights into the diversification of olfactory interactions in cichlids.
Virus-host interactomes are far from complete and would greatly benefit from the diversification of protein-interaction detection methods to allow the comprehensive exploration of the interactome space.
If species richness among plant-feeding insects has been promoted by the diversification of the plant interaction, there should be a general correlation between host diversity and species richness.
Apart from preserved conserved regions and motifs typical of Rab family, Rab7/Rab9 proteins have non-conserved sequences and structural features, that may be responsible for diversification of their functions and interactions with effectors and regulators.
The duplication of such a gene allows for divergence of one partner resulting in functional diversification and asymmetrical gain and/or loss of interactions in the complex.
Evolutionary theory focused on explaining how exaggerated offspring solicitation can be understood as resolution of parent-offspring conflict, but the evolutionary origin and diversification of different forms of family interactions remains unclear.
Overall, our analyses emphasized how the current complexity of ecological networks results from the diversification of the species and their interactions over evolutionary times.
Comparative whole-genome sequencing revealed molecular evidence for host adaptation including gene decay and diversification of proteins involved in host pathogen interactions.
