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Gene family expansion in mouse has allowed some diversification of expression patterns.
These results suggest that the expansion of the Meg gene family in maize does not include diversification of expression patterns but does include variation in expression level across homologs, with more recently-derived intact genes generally having higher expression levels.
Second, based on the evolutionary framework obtained from the above investigation, the functional diversification of expression in organs and protein-coding sequences of the duplicated PDE1C genes were examined by gene expression and molecular evolutionary analyses.
Our results implied that the evolutionary significance of the duplicated PDE1C genes in stickleback is in the diversification of expression patterns and an increase in gene dosage, rather than neofunctionalization of the coding sequences.
Overall, it appears that gene duplications found in gymnosperm C8 clade, and even the more ancient duplications at the family level (PgHB6), have not led to strong diversification of expression profiles compared to that observed in angiosperms.
The increased complexity of the APC gene structure, tied to the diversification of expression paths, suggests that land plants developed sophisticated mechanisms of APC regulation to cope with the sedentary life style and its associated environmental exposures.
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The separation of these genes may thus result in diversification of receptor expression and coassembly.
Due to the polyploidy events, mutations and gene rearrangements occurred, resulting in diversification of gene expression [ 31].
Both, positive selection between paralogs for altered C2H2 zinc finger DNA binding domains [ 59, 6] as well as diversification of the expression patterns between paralogs [ 51] has been shown for the (KRAB) ZNF family.
Diversification of the expression pattern is especially striking in the pairs #2 and # 38 (SAG28), #28 and At5g15960 (KIno; no LEA), and #1 (LEand) and #27, with r2 = 0.014, 0.043, and 0.018, respectively.
The large cluster of mouse Abp paralogues qualifies in three respects as genes that are rapidly evolving under strong positive selection, namely elevated KA/KS and a fast duplication rate, and now data showing rapid diversification of gene expression following duplication.
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