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This observation indicates that adaptation to host proteins is at least as an important factor driving HVR1 evolution in children as diversification caused by host antibodies.
The prediction of host diversification caused by phage is also supported by results from laboratory studies with coevolving bacteria and phage (e.g., [ 27, 28]).
At recent timescales, temporal clusters of diversification caused by biogeographical events can leave a signature in the genetic variation within and among the affected lineages.
The favoured scenario combining all analyses would be one early burst of phenotypic and ecological diversification caused by directional selection towards five different adaptive peaks (insectivory, carnivory, sanguivory, nectarivory and frugivory).
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Periods of rapid diversification causing shorter branches will leave reconstruction vulnerable to the node-density effect where branch lengths may be overestimated in areas of the tree with more nodes [ 75].
Subsequently, in the early to middle Miocene, diversification was caused by vicariance due to regression and plate tectonic events.
Similar to our observations, Gilmour et al. (26 ) also linked Listeria monocytogenes isolates with PFGE types that differed by <3 bands to an outbreak, on the basis of whole-genome sequencing data, which indicated that PFGE pattern diversification was caused by mobile elements.
A long diversification fuse would be caused by a long period of very low diversification followed by a rapid increase in diversification rate, while the alternative invokes a period of high levels of extinction rates producing ghost lineages that remain unsampled in a tree of only extant lineages [ 47, 48].
Calisto is the largest butterfly genus in the West Indies but its systematics, historical biogeography and the causes of its diversification have not been previously rigorously evaluated.
Teleosts diversified explosively in their early history and this burst of diversification may have been caused by genome duplication.
The transcriptomics data for the Arabidopsis accessions represent the genetic transcriptome variability caused by diversification of a common ancestor's genome.
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