Another level of redundancy may exist with regard to HS epitope(s) that could originate from diverse tissues as long as these contain the appropriate combination and arrangement of modification patterns for function.
Thus, NDRG2 may have a general function in diverse tissues as a tumor suppressor gene.
Alternative splicing may similarly regulate Bcl2 family proteins in diverse tissues, as supported by our finding that SSA induces Mcl1-S splicing in carcinoma cell lines of diverse origin.
hK10 was found to be present in diverse tissues, such as breast, ovary, and prostate as well as in many biological fluids (Liu et al, 1996; Luo et al, 1998, 2001a).
Overall, we calculated SSMIs values for 80% of the approximately 19,000 genes included in our between-method comparison with moderate confidence, and expect that many of the remaining genes could be scaled using a more diverse set of tissues, as proposed.
Intriguingly, CR enhances mitochondrial protein acetylation in diverse tissues, such as liver, heart, and kidney (Schwer et al, 2009).
It has been previously shown that p53 TSD /− mice have a diminution of adult stem cells in diverse tissues such as bone marrow, brain, and testes.
Although each CRM displays a specific spatial expression pattern with expression in diverse tissues such as various cuticle parts, the wings, legs and different structures in the head, all displayed identical temporal profiles, with reporter activation starting at 48 h APF and peaking at 72 h APF.
As might be expected, tissues as diverse as pollen, roots or leaves exhibit very large differences in gene expression, and it is therefore an analytical challenge to understand the gene expression profiles which account for their developmental differences and similarities.
Members of the DEG/ENaC family have been identified in organisms ranging from nematodes, snails, flies, vertebrates, including humans, and are expressed in tissues as diverse as kidney epithelia, muscle and neurons [1], [2].
This protein structure is not restricted to the liver cells but it is also present in the perinuclear regions of cells of tissues as diverse as kidney, heart, lung and brain (Table 1, Table 2 and Figure 4A).
