Sentence examples for diverse subtypes and from inspiring English sources

They enabled milestone discoveries in pharmacology and biochemistry ranging from the original formulation of the receptor concept, the first isolation and structural analysis of a receptor protein (the nAChR) to the identification, localization, and differentiation of its diverse subtypes and their validation as a target for therapeutic intervention.

In situ phenotyping of tumor biomarker expression and karyotyping of chromosome ploidy performed by iFISH® will shed light on additional intriguing clinical utilities and significance of diverse subtypes of CTC/DTC, and will also help guide more meaningful studies performed on the targeted single tumor cell enriched from different types of cancer patient or tumor animal models.

Therefore, many T cell lines that support HIV-1 infection were tested and compared for replication of HIV-1 isolates, including viruses that use different receptors and diverse subtypes.

High-affinity neutralising antibodies against a conserved epitope could provide protective immunity against diverse subtypes of FMDV serotype O and protect against future pandemics.

Cancer is a heterogeneous disease and many cancer types do not represent a single entity, but are composed of biologically and clinically diverse subtypes.

Src is highly expressed and activated in sarcomas of diverse subtypes, including high-grade osteosarcoma, leiomyosarcoma, synovial sarcoma and liposarcoma [ 34, 40].

In addition, iFISH enables classifying CTCs/DTCs into diverse subtypes by in situ phenotyping of the tumor biomarkers and karyotyping of chromosome ploidy (in situ PK CTC or DTC) [7].

We suggest that molecular alterations in p53 and the mTORC1 pathway play different roles in the initiation of the different endometrial cancer subtypes, but that combined p53 inactivation and mTORC1 pathway activation are unifying pathogenic features among histologically diverse subtypes of late stage aggressive endometrial tumours.

We selected two of the best compounds 45A (NBD-14009) and 46A (NBD-14010) to test against a panel of 51 Env-pseudotyped HIV-1 representing diverse subtypes of clinical isolates.

Induction of HIV-1-specific T-cell responses relevant to diverse subtypes is a major goal of HIV vaccine development.

Alternative splicing of the slo mRNA [27] as well as tissue-specific β subunits are found to give rise to diverse subtypes [38].