Sentence examples for diverse small molecules from inspiring English sources

Structurally complex and diverse small molecules can be prepared using diversity-oriented synthesis, and the split-pool strategy allows their spatial segregation on individual polymer beads, but typically in quantities that limit their usefulness.

A method for the covalent capture and screening of diverse small molecules in a microarray format.

Nonribosomal peptide and polyketide natural products are structurally diverse small molecules synthesized on complex enzyme assemblies.

Libraries of diverse small molecules are important to probe and drug discovery.

We are engineering natural product pathways, a source of structurally diverse small molecules, to biosynthesize new compounds.

A series of diverse small molecules have been designed and synthesized through structure-based drug design by taking advantage of fragment merging and elaboration approaches.

We report a 3D QSAR study of almost 300 structurally diverse small molecule antagonists of the integrin α4β1 whose biological activity spans six orders of magnitude.

Our protein list provides a starting point for systematic dissection of cytokinesis, a direction that will be greatly facilitated by also having diverse small molecule inhibitors, which we have identified.

In this paper, we report diverse small molecule inhibitors with a potential to attenuate cancer growth designed based on high-throughput virtual screening and docking using the crystal structure of SIRT1.

The performance of several structure-based design (SBD) approaches in predicting the binding affinity of diverse small molecule inhibitors co-crystallized to human renin was assessed to ascertain the modeling tool and method of choice required when dealing with structure-based lead optimization projects.

We investigated whether a screen of a large-size diverse small molecule collection could yield novel scaffolds directed at the histone demethylase family that would be useful in in vitro studies.