Sentence examples for diverse signalling pathways from inspiring English sources
The assembly of these multimolecular complexes or modules at the cellular site of action is accomplished by scaffolding proteins that have the capacity, through simultaneous interaction with multiple signalling proteins, to integrate diverse signalling pathways [ 40].
For instance, palmitoylation regulates localization and signalling activity of Ras isoforms, and hence diverse signalling pathways [9].
However, the PC12-ND6 cellular paradigm has inherent limitations, such as the lack of diversity in terms of lineages and response to diverse signalling pathways, which prevent addressing the question of how mitochondrial biogenesis is tailored to specific needs of neuronal populations upon cell fate commitment and differentiation.
Endocytosis is a key regulatory step of diverse signalling pathways, including receptor tyrosine kinase (RTK) signalling.
T3SS effectors are targeted to different subcellular compartments and affect diverse signalling pathways and physiological processes.
Activated EGFR triggers diverse signalling pathways in tumour cells (Ahmed et al, 2006; Yarden and Shilo, 2007).
Thus, RACK1 functions as an endogenous inhibitor of the Src kinase in diverse signaling pathways that regulate distinct cellular functions.
This complex phosphorylates other FA signaling and adapter proteins such as paxillin, thereby activating diverse signaling pathways in the regulation of cell migration6,7.
Lehner, B., Crombie, C., Tischler, J., Fortunato, A. & Fraser, A. G. Systematic mapping of genetic interactions in Caenorhabditis elegans identifies common modifiers of diverse signaling pathways.
The ADP-ribosyltransferase activity of ExoS and ExoT and their cellular toxicity are dependent upon association of the ART domains with 14-3-3 14-3-3 14-3-34 These are ubiquitous, abundant regulators of diverse signaling proteins, and act through hundreds of cellular targets.13,14
Enzymatic cleavage of transmembrane anchors to release proteins from the membrane controls diverse signaling pathways and is implicated in more than a dozen diseases.
