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In considering the values reported below it is important to take into account that the same event may be observed in diverse samples in a different heteroplasmic status.
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Recruitment and retention of a culturally and socioeconomically diverse sample in a longitudinal study is challenging.
As one of the first studies to examine these relationships in a US sample, these findings should be replicated in other, more diverse samples in the US and other developed nations.
The SAHA has been used in ethnically diverse samples in multiple countries [e.g. 31– 31].
Future research should attempt to include more diverse samples in order to examine the risk and risk factor of FSD in other groups.
These findings should be viewed tentatively until findings are replicated with larger and more diverse samples, in longitudinal designs that employ controls.
Therefore, additional studies in more diverse samples, in different family settings, in geographic regions outside the US Intermountain West, and among members of high-risk families with less prior research participation will be required to determine the generalizability of these findings.
Recruitment strategies were designed to produce a diverse sample in terms of race and ethnicity as well as serostatus in an effort to reflect the demographics of the San Francisco Bay Area.
Participants will be recruited from the Perth metropolitan area using a variety of recruitment methods to achieve a diverse sample in terms of age, gender, and socioeconomic status.
Recruiting one spouse from an existing cohort enabled us to select a diverse sample in terms of area of residence and occupational background.
Smaller sample sizes, especially in quite diverse samples (as in a nationwide survey) erode the poll's strength.
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