The domains are highly evolutionarily conserved, and genetic studies in model organisms such as C.elegans, Drosophila, Xenopus laevis, zebrafish, and mice have demonstrated an essential role of ILK in embryonic development and diverse physiological functions, and have confirmed tight functional linkages of ILK with integrins [2], [4].
In such a network, altering one DUSP may cause multiple functional changes of its substrates that are translated into even more diverse physiological functions in the least predictable manner.
Rhomboids are intramembrane serine proteases with diverse physiological functions in organisms ranging from archaea to humans.
Its main task is to synthesize and secrete melatonin, a nocturnal hormone with diverse physiological functions.
These enzymes have diverse physiological functions and are thus very attractive for science and industry.
Furthermore, the distinct localization of these two inhibitors in the vascular compartment indicates that they may serve diverse physiological functions during different stages of luteal angiogenesis.
Extracellular matrix (ECM) materials have diverse physiological functions by themselves and can also act as reservoirs of cytokines and growth factors, so that they can affect the cell phenotype, attachment, migration and proliferation of cells.
SYG-1 and SYG-2 are multipurpose cell adhesion molecules (CAMs) that have evolved across all major animal taxa to participate in diverse physiological functions, ranging from synapse formation to formation of the kidney filtration barrier.
Peptides in the RF-NH2 family are grouped together based on an amidated dipeptide C terminus and signal through G-protein coupled receptors (GPCRs) to influence diverse physiological functions.
It is constantly exposed to substantial challenges and exerts a potpourri of diverse physiological functions.
A number of heavy metal ions are essential in diverse physiological functions and thus are essential for life.
