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Mutations in telomerase and short telomeres must work in concert with other genetic and environmental factors to result in the diverse phenotypes with which these mutations now have been associated.
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We then explored the novel function of BCLAF1 in the γH2AX-coordinated cell fate-determining pathways under different radiation conditions including those diverse phenotypes associated with either induction of apoptosis in irreparable cells, or cell survival with active DNA repair, or cell survival toward carcinogenesis.
This further confirms that the diverse phenotypes associated with the deletion of Sec61β in distinct species are not due to divergence in the amino acid sequences, but rather they reflect different downstream effects of a conserved Sec61β function supported by the TMD.
In addition, the diverse phenotypes observed with the ST80 isolates suggest that local variants of ST80 clones are emerging in Kuwait.
Although the general role of JAZ proteins during flower development can be anticipated based on their inhibition of the JA signal transduction pathway, the diverse phenotypes associated with JA-insensitivity in different plant species suggest species-specific functions for JAZ proteins.
Animals from these two diverse phenotypes were genotyped with the Porcine SNP60K chip and compared by several approaches in order to prove the feasibility of our CNV analysis and to identify putative markers of fertility.
Hereditary diffuse leukoencephalopathy with spheroids (HDLS) is a rare, autosomal-dominant neurodegenerative disease that presents with diverse phenotypes including motor impairments such as gait dysfunction, rigidity, tremor and bradykinesia along with cognitive impairments like personality changes and dementia [ 1].
Due to the varied metabolic processes for which copper is required, there are a wide variety of copper-related diseases with diverse phenotypes.
While the M1/M2 designation is still used in the literature, the M2 subclass has expanded to include macrophages with diverse phenotypes and functions [7], [8], [10].
This chromosome instability causes karyotype variability, giving rise to aneuploid descendants with diverse phenotypes.
The Solanaceae is a family of closely related species with diverse phenotypes that have been exploited for agronomic purposes.
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CEO of Professional Science Editing for Scientists @ prosciediting.com