In sum, our results revealed highly diverse patterns of gene gain and loss among subfamilies of chemoreceptors and among species.
However, the increasing application of molecular approaches is transforming the way to categorize these tumours, since it seems that histologically comparable lesions may exhibit diverse patterns of gene expression and genomic alterations [ 5- 7, 9, 19, 20].
One such mechanism is DNA methylation that has the capacity to establish and maintain diverse patterns of gene expression from the same genome under specific temporal, spatial and environmental conditions [ 3].
The analysis of gene expression was assayed in triticale and rye by RNA-Seq analysis of 454 sequence sets and members of the gene family were found to have diverse patterns of gene expression in the different tissues that were sampled in rye and in triticale, the hybrid hexaploid species derived from wheat and rye.
Principal component analysis (PCA) of gene expression in the spleen (Figure 2B) showed that early (day 7) iCT frogs contributed the most diverse patterns of gene-expression of any group, as well as showing the highest prevalence and intensities of infection (Figure 1).
Overall, the wheat and barley array data show a diverse pattern of caleosin gene expression in various tissues, and represent independent data sets that corroborate some of the tissue-specific caleosin gene expression patterns observed for rye and triticale.
Thus RT-PCR studies indicate that tumour cells of similar epithelial origin display a diverse pattern of NOS gene family expression, and parallel biochemical studies clearly indicate that such expression does not always result in measurable enzymic activity leading to the generation of NO.
Overall, these results demonstrate a very diverse pattern of tissue-specific expression of the caleosin genes.
The diverse pattern of occurrence together with conserved insertions in rather unrelated species strongly suggests lateral gene transfer.
Extensive gene expression data for nine of the fourteen P. falciparum E2s suggest a diverse pattern of steady state mRNA accumulation at different stages of intraerythrocytic development.
