Sentence examples for diverse pathologies including from inspiring English sources

Dysfunction of PPAR-γ is implicated in diverse pathologies including diabetes, glomerulosclerosis, atherosclerosis and pulmonary artery hypertension (PAH) [ 31].

Immune dysregulation results in diverse pathologies including autoimmune disease, chronic inflammatory disorders, allergies as well as immune deficiencies and cancer.

Lipids regulate diverse cellular processes including metabolic, inflammatory, and innate immune responses, and imbalances in lipid signaling pathways contribute to diverse pathologies including insulin resistance and cardiovascular disease [ 39- 41].

Because PKCα is central to the function of this and many other pathways, its dysfunction or excess activity can trigger diverse pathologies, including inflammation, cancer, diabetes, cardiovascular anomalies, and autoimmune disease.

The threshold contrast, at which a pattern of stripes is just visible, is a measure of a different visual function that can pick up deficits in diverse pathologies including retinal diseases [ 11, 30– 30].

This review focuses on recent developments to engineer bacteria for the treatment of diverse human pathologies, including inflammatory bowel diseases, autoimmune disorders, cancer, metabolic diseases and obesity, as well as to combat bacterial and viral infections.

In the initial report, in a heterogeneous Japanese sample of 13 men and 31 women, with diverse urological pathologies including neurogenic bladder and benign prostatic hyperplasia, the rs4994 SNP was not associated with LUTS (odds ratio [OR], 1.20; 95% confidence interval [CI], 0.32 4.47).

Aberrant methylation of CpG islands in the promoter region of tumor suppressor genes (TSGs) are linked to gene silencing, while deregulation of miRNAs − small, noncoding RNAs species that regulate gene expression − is implicated in diverse human pathologies, including lung cancer (reviewed in [ 125- 128]).

Overall, 4% of the study participants were diagnosed with chronic debilitating illness, the causes of which include a diverse spectrum of pathologies, including malnutrition and HIV infection.

Perturbations in Hcy metabolism are reflected by altered levels of circulating plasma Hcy concentrations which correlate with a diverse range of pathologies including vascular dysfunction, neurodegenerative disorders, congenital defects and diabetes, together with renal and hepatic syndromes [40].

In line with the putative role of sirtuins in promoting longevity, a large body of evidence has revealed major roles for individual sirtuins in suppressing diverse age-associated pathologies, including cancer and metabolic diseases (Giblin et al., 2014).