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Candidate genes were screened in a subset of 27 diverse lines (DL), selected to be representative of the genetic and phenotypic diversity in the association panel, in order to identify highly polymorphic regions for further association studies.
Except for one black and one white department head and me, all others seemed to segregate themselves along diverse lines.
Those families that contain rather diverse lines have been divided into subfamilies, the number of subfamilies in each family indicating the amount of evolutionary divergence that has occurred.
Genetically diverse lines of organisms can be crossed in such a way to produce different combinations of alleles in one line.
A growing number of scientists, finding multiple species of hominids that overlapped in time, contend that in response to new or changed circumstances hominids evolved along many diverse lines -- a bush with many branches.
This evaluation of Waddington's pictorial legacy reveals that there are highly diverse lines of traditions in the life sciences, which are deeply rooted in Waddington's methodological work.
In recent years, a wealth of evidence taken from comparisons between the skeletons of these dinosaurs and those of birds has been supplemented by diverse lines of evidence in support of the same evolutionary relationship.
Whether in reference to domestication or evolution at large, the challenge of reconstructing the past can be met by drawing careful inferences from diverse lines of evidence (Wilkes 2004; Zeder et al. 2006a, b; Burger et al. 2008).
Schmitt and Pilcher (2004) recommend that to support the claim for an EPA, evidence must be marshaled from eight disciplinarily diverse lines of support: theoretical, psychological, medical, genetic, physiological, phylogenetic, hunter-gatherer, and cross-cultural evidence.
However, diverse lines of evidence indicate that polypharmacological agents, i.e. those that act simultaneously at various protein targets, might show better profiles than selective ligands, regarding both efficacy and side effects.
The molecular basis of addiction remains poorly understood, but diverse lines of evidence suggest that neurotrophins (BDNF, NT-3 and NT-4) play a role in the regulation of synaptic plasticity.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com